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	Provedor de dados Biol. Res. (1) BJMBR (1) Autor Baxmann,A.C. (1) Heilberg,I.P. (1) MAO,ZHIGUO (1) MEI,CHANGLIN (1) Nishiura,J.L. (1) Vendramini,L.C. (1) WANG,LI (1) WANG,LIMING (1) XIONG,XISHAN (1) ZHANG,TONG (1) Mais... Palavra-chave ADPKD (2) Caffeine (1) Cyclic AMP (1) Han: SPRD rat (1) Mycophenolate mofetil (1) Nutrition (1) Polycystic kidneys (1) Rapamycin (1) Renal volume (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Journal article (1) Ano 2012 (1) 2009 (1) País Brazil (1) Chile (1) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Caffeine intake by patients with autosomal dominant polycystic kidney disease BJMBR Vendramini,L.C.; Nishiura,J.L.; Baxmann,A.C.; Heilberg,I.P.. Because caffeine may induce cyst and kidney enlargement in autosomal dominant polycystic kidney disease (ADPKD), we evaluated caffeine intake and renal volume using renal ultrasound in ADPKD patients. Caffeine intake was estimated by the average of 24-h dietary recalls obtained on 3 nonconsecutive days in 102 ADPKD patients (68 females, 34 males; 39 ± 12 years) and compared to that of 102 healthy volunteers (74 females, 28 males; 38 ± 14 years). The awareness of the need for caffeine restriction was assessed. Clinical and laboratory data were obtained from the medical records of the patients. Mean caffeine intake was significantly lower in ADPKD patients versus controls (86 vs 134 mg/day), and 63% of the ADPKD patients had been previously aware of caffeine... Tipo: Info:eu-repo/semantics/article Palavras-chave: Polycystic kidneys; ADPKD; Cyclic AMP; Caffeine; Nutrition; Renal volume. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000900007 Mycophenolate mofetil versus Rapamycin in Han: SPRD rats with Polycystic Kidney Disease Biol. Res. ZHANG,TONG; WANG,LI; XIONG,XISHAN; MAO,ZHIGUO; WANG,LIMING; MEI,CHANGLIN. Objective: We aimed to explore the effect of Mycophenolate mofetil (MMF) on loss of renal function and cyst progression compared to rapamycin in Han: SPRD rats. We also sought to assess whether the effect of combination therapy of MMF plus rapamycin was better than that of monotherapy. Methods: Sixty heterozygous (Cy/+) and littermate control (+/+) male Han: SPRD rats were weaned at 4 weeks of age, then divided into four groups randomly to receive different treatments by intragastric administration for 2 months: vehicle-treated group as control, MMF-treated group (20mg/kg/day), rapamycin-treated group (2mg/kg/day), and MMF+Rapa- treated group (MMF 20mg/kg/day plus Rapamycin 2mg/kg/day). Resulls: After 2 months of treatment, rapamycin caused a 22 % decrease... Tipo: Journal article Palavras-chave: ADPKD; Han: SPRD rat; Mycophenolate mofetil; Rapamycin. Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000400005 Registros recuperados: 2 Primeira ... 1 ... Última

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